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OCT angiography in the mouse: A novel evaluation method for vascular pathologies of the mouse retina.

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Münster – mechentel news – To investigate the application of optical coherence tomography (OCT) angiography in the retinas of healthy mice and to evaluate choroidal neovascularization (CNV) in a mouse model of laser-induced CNV, C57BL/6J mice aged 18-25 weeks were examined using the spectral-domain optical coherence tomography device RTVue XR Avanti (Optovue, Inc, Fremont, California, […]

Detection of West Nile virus and tick-borne encephalitis virus in birds in Slovakia, using a universal primer set.

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Košice – mechentel news – West Nile virus (WNV) is a mosquito-borne neurotropic pathogen that presents a major public health concern. Information on WNV prevalence and circulation in Slovakia is insufficient. Oral and cloacal swabs and bird brain samples were tested for flavivirus RNA by RT-PCR using newly designed generic primers. The species designation was […]

The pros and cons of vertebrate animal models for functional and therapeutic research on inherited retinal dystrophies.

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Nijmegen – mechentel news – Over the last decade, huge progress has been made in the understanding of the molecular mechanisms underlying inherited retinal dystrophy (IRD), as well as in the development and implementation of novel therapies, especially in the field of gene therapy. The use of mutant animal models, either naturally occurring or generated […]

Microscopic Lesions in Canine Eyes with Primary Glaucoma.

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North Grafton – mechentel news – Although the clinical classification of primary glaucoma in dogs is quite simple, the phenotypes of glaucoma in most of the species are indeed multiple. Ophthalmologists can often evaluate the dynamic changes of clinical signs at different times in the course of the disease, whereas pathologists are often presented with […]