Dependence of the corneal thickness of IOP in healthy dogs eye
Seoul – mechentel news – Scientists from the Department of Veterinary Clinical Sciences, College of Veterinary Medicine and BK21 Program for Veterinary Science, Seoul National University, South Corea, demonstrated that, the Central corneal thickness (CCT) showed two core changes according to increased IOP. CCT can be a promising source of glaucoma monitoring and diagnosis. To evaluat changes to CCT according to experimental adjustment of intraocular pressure (IOP) in canine eyes and to adjust and measure IOP, Y-W. Park et al. cannulated each eye with two 26-gauge needles under inhalant anesthesia. One needle was connected to a pressure transducer and the other to an adjustable bag of physiologic saline. IOP was stepwise increase from 10 mmHg to 70 mmHg in 10 mmHg increments (Group T). IOP was maintained at 15 mmHg (Group C15), 30 mmHg (Group C30), 45 mmHg (Group C45), 60 mmHg (Group C60) and 75 mmHg (Group C75) during the experiment. CCT was measured with an ultrasonic pachymeter every 10 mins after the cannulation. There was a significant difference in effect of the time on CCT (P<0.001) and difference in CCT (dCCT; P<0.001) between groups. The CCT of group C15 remained constant during the experiment. However, groups T showed an initial decrease and then an increase after passing a lowest point. Group C30 showed decreasing values for 30 mins, after which values remained constant. Group C45 was not changed for 40 min and then increased. Group C60 was not changed for 20 min and then increased. Group C75 showed a steady increase. The authors concluded in the issue of september of Journal of Veterinary Medical Science, that this study provides essential basic data to enable further investigation into the association of IOP and CCT in dogs.
Autoren: Park YW, Jeong MB, Lee ER, Lee Y, Ahn JS, Kim SH, Seo K. Korrespondenz: Young-Woo Park, Department of Veterinary Clinical Sciences, College of Veterinary Medicine and BK21 Program for Veterinary Science, Seoul, South Korea. Studie: Acute Changes of Central Corneal Thickness According to Experimental Adjustment of Intraocular Pressure in Normal Canine Eyes. Quelle: J Vet Med Sci. 2013 Jul 16 doi: 10.1292/jvms.13-0174. Web: https://www.jstage.jst.go.jp/article/jvms/advpub/0/advpub_13-0174/_article